By car, easily reached via the Inntal Motorway A12 (exit Zillertal). From there, over the main road B169 towards Mayrhofen.
By train: to railroad station Jenbach, continuing your way to Mayrhofen with the nostalgic "Zillertalbahn" (Zillertal Train) or by bus which also departs from Jenbach.
Innsbruck Airport is only 70km away, Munich Airport 190km.